The Brazilian Center for Research in Energy and Materials (CNPEM), with support from the São Paulo Research Foundation (FAPESP), is offering two postdoctoral fellowships for work to develop new methods in the area of cryogenic electron microscopy (cryoEM). The project will take place in the Cryogenic Electron Microscopy Laboratory (Nanobiotechnology Division) at LNNano/CNPEM.
One postdoctoral position is dedicated to developing methods to optimize data processing in our cryoEM data analysis pipeline; the focus is on efficient processing of large datasets, particularly 4D processing, related to the structural variability of proteins on the global and local scale.
The other postdoctoral opportunity will focus on developing devices and methods in time-resolved cryoEM. This technique is used to study macromolecular complexes that are out of equilibrium through rapid freezing of reactions between biological macromolecules.
The selected candidates will also be responsible for using these new methodologies to support our efforts in different projects related to structural biology. CNPEM is equipped with cutting-edge microscopes for cryoEM which make it possible to obtain the structures of biological complexes with atomic resolution.
To apply, send your resume and letter of recommendation to the following email addresses by December 10, 2023: Marin van Heel (marin.vanheel@lnnano.cnpem.br) and Rodrigo Portugal (rodrigo.portugal@lnnano.cnpem.br).
Links about our group and research we are involved in
- https://g1.globo.com/sp/campinas-regiao/noticia/pesquisador-suico-candidato-ao-nobel-de-quimica-desenvolve-tecnica-vencedora-em-campinas.ghtml
- https://cnpem.br/enzimas-em-forma-de-borboleta-revelam-detalhes-ineditos-do-metabolismo-de-bacteria-probiotica-do-intestino-humano/
- https://sv-se.facebook.com/CNPEM/posts/5899333080092799
- https://lnnano.cnpem.br/cnpem-revela-inedita-estrutura-do-virus-mayaro-2/
- https://cnpem.br/pesquisa-do-cnpem-elucida-primeira-estrutura-de-enzima-dentro-da-mitocondria/
This opportunity is open to Brazilian as well as non-Brazilian candidates. The successful candidates will receive FAPESP Postdoctoral Fellowship funding of R$ 9,047.40 per month and a technical reserve equivalent to 10% of the yearly grant amount for unforeseen expenses which are directly related to research activity.
The requirements for this opportunity are as follows:
- undergraduate diploma in physics, computation, engineering, mathematics, or related subjects
- must meet all FAPESP postdoctoral scholarship requirements
- experience managing HPC systems and Windows/Linux servers is desirable.
About the project
This project is part of a FAPESP Thematic Project in cryogenic electron microscopy addressing the development of new methodologies and the study of macromolecules using this technique.
About CNPEM
A sophisticated and effervescent environment for research and development, unique in Brazil and present in few scientific centers in the world, the Brazilian Center for Research in Energy and Materials (CNPEM) is a private non-profit organization, under the supervision of the Ministry of Science, Technology and Innovation (MCTI). The Center operates four National Laboratories and is the birthplace of the most complex project in Brazilian science – Sirius – one of the most advanced synchrotron light sources in the world. CNPEM brings together highly specialized multi-thematic teams, globally competitive laboratory infrastructures open to the scientific community, strategic lines of investigation, innovative projects in partnership with the productive sector and training of researchers and students. The Center is an environment driven by the search for solutions with impact in the areas of Health, Energy and Renewable Materials, Agro-environment, and Quantum Technologies. As of 2022, with the support of the Ministry of Education (MEC), CNPEM expanded its activities with the opening of the Ilum School of Science. The interdisciplinary higher course in Science, Technology and Innovation adopts innovative proposals with the aim of offering excellent, free, full-time training with immersion in the CNPEM research environment. Through the CNPEM 360 Platform, it is possible to explore, in a virtual and immersive way, the main environments and activities of the Center, visit: https://pages.cnpem.br/cnpem360/.
