The 9th Brazil School for Single Particle Cryo-EM
The 9th Brazil School for Single Particle Cryo-EM will follow the successful pattern of the previous school in this series that was interrupted by five years due to the Covid-19 pandemic.
The course participants will learn the processing of single particles from optimizing the data collection and automatic particle selection, through the pre-processing, 2D-3D particle alignments, 3D reconstruction, 4D image analysis of data-sets with mixed populations, up to the interpretation of the data and fitting of known X-ray structures.
The Multivariate-Statistical-Analysis (MSA) plays a crucial role in most aspects of the data processing. This year, special emphasis will also be placed on new fundamental insights in the Foundations of Physics that surfaced with the advanced use of new sensors that allow the detection of each individual electron arriving in the sensor.