The Brazilian Center for Research in Energy and Materials (CNPEM), with support from the São Paulo Research Foundation (FAPESP), is offering a postdoctoral fellowship in molecular and cellular cancer biology within the thematic project sphere “Microenvironment metabolism and the role of metabolic exchanges in tumor progression.” Work on this project will be conducted within the Molecular and Cellular Sociology Laboratory at the Brazilian Biosciences National Laboratory (LNBio).
Project title: Glutaminase 1 and remodeling of the immune microenvironment in triple-negative breast cancer
The fellowship is linked to the thematic project which includes among its objectives studying the impact of glutamine metabolism on the profile of immune cells infiltrated within the tumor microenvironment. The selected candidate will continue the research underway in the laboratory, focusing on mechanisms associated with the response to co-treatment with anti-PD1 therapy and a glutaminase inhibitor in syngeneic mouse models of triple-negative breast cancer.
Requirements
- Doctorate in biology, biochemistry, biomedicine, pharmacy, biotechnology, or related areas.
- Solid experience with animal experimentation, especially in tumor models.
- Strong experience with cell culture and gene manipulation (KD and/or KO), as well as 3D culture.
- Familiarity with omics approaches.
- Advanced English skills.
How to apply
Interested candidates should send an abbreviated resume in the format recommended by FAPESP, a letter of introduction (2 pages maximum) explaining their interest in the position and briefly summarizing their relevant experience, and a letter of recommendation via email to sandra.dias@lnbio.cnpem.br by March 15, 2025.
About the scholarships
This is a FAPESP fellowship in the postdoctorate modality. To learn more about this modality, visit the FAPESP website at: https://fapesp.br/valores/bolsasnopais.
Please direct any questions to sandra.dias@lnbio.cnpem.br.
About CNPEM
The Brazilian Center for Research in Energy and Materials (CNPEM) is home to a state-of-the-art, multi-user and multidisciplinary scientific environment and works on different fronts within the Brazilian National System for Science, Technology and Innovation. A social organization overseen by the Ministry of Science, Technology and Innovation (MCTI), CNPEM is driven by research that impacts the areas of health, energy, renewable materials, and sustainability. It is responsible for Sirius, the largest assembly of scientific equipment constructed in the country, and is currently constructing Project Orion, a laboratory complex for advanced pathogen research. Highly specialized science and engineering teams, sophisticated infrastructure open to the scientific community, strategic lines of investigation, innovative projects involving the productive sector, and training for researchers and students are the pillars of this institution that is unique in Brazil and able to serve as a bridge between knowledge and innovation. It is responsible for operating the Brazilian Synchrotron Light (LNLS), Biosciences (LNBio), Nanotechnology (LNNano), and Biorenewables (LNBR) National Laboratories, as well as the Ilum School of Science, which offers a bachelor’s degree program in science and technology with support from the Ministry of Education (MEC).
